Jun 25 17 8:08 AM

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Lyme Disease Tests

Lyme disease tests are used to determine if a person with characteristic signs and symptoms has been infected by the bacteria Borrelia burgdorferi or Borrelia mayonii. The tests detect antibodies produced by the immune system in response to the infection.

Lab tests can detect two different classes of antibody, IgM and IgG.

  • Borrelia IgM (immunoglobulin M) antibodies are usually detectable in the blood about two to three weeks after exposure. IgM levels increase to maximum concentrations at about six weeks and then begin to decline.

  • IgG (immunoglobulin G) antibodies are not detectable until several weeks after exposure, increase to maximum levels at about four to six months, and may remain at high levels for several years.

The Centers for Disease Control and Prevention (CDC) recommends that two different methods be used to detect these antibodies and to confirm a diagnosis of Lyme disease. The initial test is intended to be very sensitive so that it will detect as many cases of Lyme disease as possible. However, it may be positive when a person does not have Lyme disease but has some other condition, such as a different tick-borne disease, syphilis, or an autoimmune disorder such as lupus. Therefore, if the result of the initial test is positive, a second test that uses a different method is used to confirm the findings. The following chart illustrates the recommended steps:


Also see : Autoimmune Diseases

Note the use of “ autoimmune “ above.


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Last Edited By: Sir Loin Jun 25 17 8:29 AM. Edited 2 times